<!DOCTYPE html>
<html lang="en">

<head>
    <meta charset="UTF-8">
    <meta name="viewport" content="width=device-width, initial-scale=1.0">
    <title>Document</title>
    <style>
        * {
            padding: 0;
            margin: 0;
        }

        .big {
            width: 80%;
            height: 600px;
            background-color: red;
            margin: 0 auto;
        }

        .big_left {
            width: 350px;
            height: 500px;
            background-color: aqua;
            float: left;
            margin-right: 150px;
        }

        .big_right {
            width: 500px;
            height: 500px;
            background-color: yellow;
            float: left;
        }

        .up {
            width: 200px;
            height: 200px;
            background-color: azure;
            margin-bottom: 50px;
            margin-left: 50px;
        }

        .down {
            width: 200px;
            height: 200px;
            background-color: rgb(11, 234, 234);
            margin-left: 200px;
        }
    </style>
</head>

<body>
    <div class="big">
        <!-- left -->
        <div class="big_left"></div>
        <!-- right -->
        <div class="big_right">
            <!-- 上 -->
            <div class="up"></div>
            <!-- 下 -->
            <div class="down"></div>
        </div>
    </div>
</body>

</html>